Post by Joann on Jan 17, 2011 11:43:37 GMT -5
I came across this today:
Proposed sheep milk withdrawal times after antibiotic use
//17 Jan 2011
Researchers at the Veterinary Faculty of the University of Thessaly in Greece reviewed the proposals for withdrawal period of sheep milk for some commonly used veterinary medicinal products.
The review was based on studies performed in Greece. Several studies have been performed to establish milk withdrawal time for the following veterinary medicinal products, commonly used in the therapeutics of sheep: lincomycin, spectinomycin, procaine penicillin G, dihydrostreptomycin, kanamycin, oxytetracycline, trimethoprim and sulfadiazine, albendazole. For oxytetracycline, two pharmaceutical forms were tested, specifically long-acting injectable solution and spray. For albendazole, the pharmaceutical form of oral suspension was tested. For all the other antimicrobials, the pharmaceutical form of injectable solution was tested.
Residues in milk
The animal phase of all the trials was performed at the Veterinary Faculty of the University of Thessaly. Each product was administered at the highest recommended dose and the frequency currently licensed for administration to sheep. Subsequently, either liquid chromatography or liquid chromatography–mass spectrophotometry was used under GLP principles and as required each time, in order to establish residues of each antibiotic in milk. Most of the analytical work was carried out at GLP accredited laboratories.
Recommended withdrawal times
The researchers took the legally established minimum residue levels of each antibiotic and their concentrations detected in sheep milk were into account and defined the following withdrawal periods:
lincomycin and spectinomycin inj. sol.: 4 milkings
procaine penicillin G and dihydrostreptomycin inj. sol.: 5 milkings
dihydrostreptomycin inj. sol.: 5 milkings
kanamycin inj. sol.: 4 milkings
oxytetracycline long-acting inj. sol.: 16 milkings
oxytetracycline spray: 0 milkings
trimethoprim and sulfadiazine inj. sol.: 7 milkings
albendazole or. susp.: 7 milkings after last administration of each test product.
The above results provide standards and will help veterinarians to use the various veterinary pharmaceutical products in the therapeutics of dairy ewes.
Joann
Proposed sheep milk withdrawal times after antibiotic use
//17 Jan 2011
Researchers at the Veterinary Faculty of the University of Thessaly in Greece reviewed the proposals for withdrawal period of sheep milk for some commonly used veterinary medicinal products.
The review was based on studies performed in Greece. Several studies have been performed to establish milk withdrawal time for the following veterinary medicinal products, commonly used in the therapeutics of sheep: lincomycin, spectinomycin, procaine penicillin G, dihydrostreptomycin, kanamycin, oxytetracycline, trimethoprim and sulfadiazine, albendazole. For oxytetracycline, two pharmaceutical forms were tested, specifically long-acting injectable solution and spray. For albendazole, the pharmaceutical form of oral suspension was tested. For all the other antimicrobials, the pharmaceutical form of injectable solution was tested.
Residues in milk
The animal phase of all the trials was performed at the Veterinary Faculty of the University of Thessaly. Each product was administered at the highest recommended dose and the frequency currently licensed for administration to sheep. Subsequently, either liquid chromatography or liquid chromatography–mass spectrophotometry was used under GLP principles and as required each time, in order to establish residues of each antibiotic in milk. Most of the analytical work was carried out at GLP accredited laboratories.
Recommended withdrawal times
The researchers took the legally established minimum residue levels of each antibiotic and their concentrations detected in sheep milk were into account and defined the following withdrawal periods:
lincomycin and spectinomycin inj. sol.: 4 milkings
procaine penicillin G and dihydrostreptomycin inj. sol.: 5 milkings
dihydrostreptomycin inj. sol.: 5 milkings
kanamycin inj. sol.: 4 milkings
oxytetracycline long-acting inj. sol.: 16 milkings
oxytetracycline spray: 0 milkings
trimethoprim and sulfadiazine inj. sol.: 7 milkings
albendazole or. susp.: 7 milkings after last administration of each test product.
The above results provide standards and will help veterinarians to use the various veterinary pharmaceutical products in the therapeutics of dairy ewes.
Joann